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Important Research Notice

Not for human consumption. This product is sold exclusively for research and educational purposes. It is not intended to diagnose, treat, cure, or prevent any disease.

All clinical trial data and research findings presented on this page are sourced from peer-reviewed journals and official publications. They are provided for educational reference only and should not be interpreted as medical advice or product claims.

By purchasing this product, you confirm that you are a qualified researcher and will use it in accordance with all applicable laws and regulations.

VIP 10 MG research peptide vial - StarBio COA published
  • Arrives Thu, Oct 22 – Tue, Oct 27Free standard shipping on orders over $100
  • Free shipment protectionLost, stolen, or damaged? We replace it, on us.
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VIP

Cellular Peptide

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Vasoactive intestinal peptide, a 28-residue neuropeptide that acts on the VPAC1 and VPAC2 receptors. It is used in research on smooth-muscle relaxation, immune regulation and circadian signaling. For in vitro laboratory research use only.

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Mass
Quantity
Third-party tested batchCOA on fileShips from the USALost or damaged? Reshipped free
  • Arrives Thu, Oct 22 – Tue, Oct 27Free standard shipping on orders over $100
  • Free shipment protectionLost, stolen, or damaged? We replace it, on us.
  • Overnight and 2-day optionsPick your speed at checkout
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Certificate of Analysis

Third Party Tested ISO/IEC 17025 ACCREDITED

LATESTISO 170257× TESTING
ID ✓
IDENTITY & CONTENT VERIFIED

✓ Passed full QC panel

Variant VIP 10 mg
Test report Janoshik #136378
Labeled 10 mg
📄 View COA
Technical specifications

Compound Information

Molecular profile

What is VIP?

Type 28-residue neuropeptide, C-terminally amidated
CAS number
37221-79-7
Molecular weight
3,326.8 g/mol
Amino acids
28
Formula
C147H237N43O43S
Sequence 28 residues
  1. H
  2. S
  3. D
  4. A
  5. V
  6. F
  7. T
  8. D
  9. N
  10. Y
  11. T
  12. R
  13. L
  14. R
  15. K
  16. Q
  17. M
  18. A
  19. V
  20. K
  21. K
  22. Y
  23. L
  24. N
  25. S
  26. I
  27. L
  28. N
  29. NH2
Storage requirements

Stability information

-20°C Lyophilized powder Long-term storage
2–8°C Reconstituted Short term
Handling
  • Protect from light
  • Avoid repeated freeze-thaw cycles

Conditions apply to sealed research vials as supplied. Batch details are on the Certificate of Analysis above.

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Sources & References

Peer-reviewed research

Frontiers in oncology

Vasoactive intestinal peptide-VIPR2 signaling regulates tumor cell migration

2022 · PMID: 36237322 · DOI: 10.3389/fonc.2022.852358

Asano S, Yamasaka M, Ozasa K, Sakamoto K, Hayata-Takano A, Nakazawa T, et al.

View Source ↗
Current protein & peptide science

Heparin Oligosaccharides as Vasoactive Intestinal Peptide Inhibitors via their Binding Process Characterization

2024 · PMID: 38284716 · DOI: 10.2174/0113892037287189240122110819

Li M, Xue Y, Chi L, Jin L

View Source ↗
Annals of the New York Academy of Sciences

Vasoactive intestinal peptide. Messenger in a neuroimmune axis

1990 · PMID: 2165755 · DOI: 10.1111/j.1749-6632.1990.tb40472.x

Wenger GD, O'Dorisio MS, Goetzl EJ

View Source ↗
Microcirculation (New York, N.Y. : 1994)

Vasoactive Intestinal Peptide: Another Player in Adipose Tissue Blood Flow Regulation?

2025 · PMID: 40946317 · DOI: 10.1111/micc.70026

Sotornu00edk R, Mu00e9nard J, Brassard P, Gagnon-Auger M, Baillargeon JP, Ardilouze JL

View Source ↗
Annals of the New York Academy of Sciences

Vasoactive intestinal peptide and renin secretion

1988 · PMID: 3291698 · DOI: 10.1111/j.1749-6632.1988.tb27000.x

Porter JP, Ganong WF

View Source ↗
Amino acids

Vasoactive intestinal peptide: a neuropeptide with pleiotropic immune functions

2013 · PMID: 22139413 · DOI: 10.1007/s00726-011-1184-8

Delgado M, Ganea D

View Source ↗
Nature

Feeding-dependent VIP neuron-ILC3 circuit regulates the intestinal barrier

2020 · PMID: 32050257 · DOI: 10.1038/s41586-020-2039-9

Talbot J, Hahn P, Kroehling L, Nguyen H, Li D, Littman DR

View Source ↗
The Journal of pharmacology and experimental therapeutics

Development of simplified vasoactive intestinal peptide analogs with receptor selectivity and stability for human vasoactive intestinal peptide/pituitary adenylate cyclase-activating polypeptide receptors

2005 · PMID: 15994369 · DOI: 10.1124/jpet.105.088823

Igarashi H, Ito T, Mantey SA, Pradhan TK, Hou W, Coy DH, et al.

View Source ↗
Gastro hep advances

The G Protein-Coupled Receptor, VPAC1, Mediates Vasoactive Intestinal Peptide-Dependent Functional Homeostasis of the Gut Microbiota

2022 · PMID: 36910129 · DOI: 10.1016/j.gastha.2021.11.005

Ericsson AC, Bains M, McAdams Z, Daniels J, Busi SB, Waschek JA, et al.

View Source ↗
The Journal of biological chemistry

Identification and characterization of vasoactive intestinal peptide receptor antagonists with high-affinity and potent anti-leukemia activity

2026 · PMID: 41478571 · DOI: 10.1016/j.jbc.2025.111127

Wang Y, Sen-Majumdar A, Li JM, Sarkar S, Passang T, Mecorapaj S, et al.

View Source ↗
American journal of physiology. Gastrointestinal and liver physiology

Expression and localization of VPAC1, the major receptor of vasoactive intestinal peptide along the length of the intestine

2017 · PMID: 28385693 · DOI: 10.1152/ajpgi.00081.2017

Jayawardena D, Guzman G, Gill RK, Alrefai WA, Onyuksel H, Dudeja PK

View Source ↗

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